Pacific Biosciences of California designs, develops and manufactures sequencing systems. Co.'s commercial product includes the PacBio RS System, PacBio RS II System, and the Sequel System. The PacBio RS II and Sequel Systems conduct, monitor, and analyze biochemical sequencing reactions. The PacBio RS II and Sequel instruments are integrated units that include optics, automated liquid handling, a touchscreen control interface and computational hardware and software. Customers purchase proprietary consumable products to run either the PacBio RS II System or Sequel System. Co.'s consumable products include its proprietary Single Molecule, Real-Time Cells and reagent kits.